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- (1)
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- (1)
- (1)
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Filtered Search Results
Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Intended for research use only, this compound effectively inhibits estrogen and progesterone production. It has demonstrated efficacy in preventing the development of various spontaneous neoplasms and reducing parasite burden in animal models.
- Potent, selective, and nonsteroidal aromatase inhibitor
- Inhibits estrogen production in hamster ovarian slices
- Inhibits progesterone production
- Prevents development of benign and malignant spontaneous mammary neoplasms
- Reduces incidence of spontaneous hepatocellular tumors
- Reduces parasite burden in male and female mice
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) | 125941-87-9 | 99.8% | 324.24 | 1 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist, also acting as a potent human 5-HT2C receptor agonist. It binds with high affinity to various serotonin receptors and inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels. This compound can reverse inhibitory effects on NLRP3 expression and inflammasome pathways in BV-2 cells, and has been used in studies of neurological disorders like psychosis and Parkinson's disease.
- Potent and selective dopamine D1-like receptor antagonist
- Potent and high efficacy human 5-HT2C receptor agonist
- Binds with high affinity to 5-HT2 and 5-HT1C receptors
- Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels
- Used in studies of neurological disorders like psychosis and Parkinson's disease
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Arg1-in-1 hydrochloride | 90.0% | C11H22BClN2O4 | 1 MG
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ARG1-IN-1 hydrochloride is an orally active arginase inhibitor with an IC50 value of 29 nM. It can inhibit serum arginase activity and increase arginine levels in mouse tumor models, making it applicable for tumor research.
- Orally active arginase inhibitor.
- Inhibits serum arginase activity.
- Increases arginine levels in mouse tumor models.
- Applicable for tumor research.
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Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 250 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. It can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Inhibits mRNA and protein levels of TXNIP.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and blocks hepatic glucose output in mice.
- Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.
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Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | ≥97.0% | 379.88 | C19H26ClN3O3 | 10 MG
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BMY-25368 hydrochloride is a research reagent used as a histamine H2 receptor antagonist and gastric acid secretion inhibitor. Supplied as a hydrochloride salt with documented molecular and purity data, it is intended for preclinical in vitro and in vivo studies where receptor antagonism or gastric secretion modulation is required.
- Histamine H2 receptor antagonist for gastric acid secretion studies.
- Hydrochloride salt form for improved solubility and stability.
- High purity (≥97.0% by NMR) suitable for research use.
- Verified molecular weight (379.88) and formula for accurate dosing.
- Available in small-scale quantities for preclinical experiments.
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Medchemexpress LLC Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Flavoxate hydrochloride | 3717-88-2 | 99.7% | 1 ML
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Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.1% | 321.93 | 500 MG
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Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which is known to regulate fatty acid synthesis.
- Tricyclic diterpene molecule
- Extracted from the bark of pine trees
- Cannabinoid receptor type 1 (CB1) agonist
- Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
- Suppresses transcriptional activity of androgen receptor
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Medchemexpress LLC Nimustine hydrochloride | 55661-38-6 | MFCD01676942 | 98.2% | C9H14Cl2N6O2 | 10MG
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Nimustine hydrochloride is the hydrochloride salt of nimustine, an alkylating antitumor agent used in research to induce DNA damage and study DNA-damage response pathways. It produces DNA double-strand breaks and inter-strand crosslinks and activates signaling cascades involved in the DNA damage response.
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Medchemexpress LLC Ly 303511 hydrochloride | 2070014-90-1 | 98.9% | 342.82 g·mol⁻¹ | C19H19ClN2O2 | 10 MG
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LY 303511 hydrochloride is a research-grade small molecule (CAS 2070014-90-1) that acts as a structural analogue of LY294002; it enhances TRAIL sensitivity in SHEP-1 neuroblastoma cells and reversibly blocks potassium currents in MIN6 insulinoma cells. Supplied as a 10 mg solid with high purity for in vitro studies. Store sealed and protected from moisture.
- High purity (98.9%) suitable for screening and biochemical assays.
- Compact 10 mg pack for dose-response and early-stage experiments.
- Solid form stable under recommended storage temperatures when sealed.
- Documented activity on TRAIL sensitivity and potassium current modulation.
- CAS number provided for precise chemical identification.
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Medchemexpress LLC SB-277011 (hydrochloride) | 215804-67-4 | 99.6% | 475.02 | 25 MG
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SB-277011 hydrochloride is a potent, selective, orally bioavailable, and brain-penetrant dopamine D3 receptor (D3R) antagonist. It demonstrates 80- to 100-fold selectivity over other dopamine receptors.
- Ki values of 10.7 nM and 11.2 nM at rodent and human D3R, respectively.
- Selectivity over D2, 5-HT1B, and 5-HT1D receptors.
- Oral bioavailability of 43% and a half-life of 2.0 h in rats.
- High brain-penetrant (brain:blood ratio of 3.6:1).
- Reverses quinelorane effects in the nucleus accumbens at 3 mg/kg (p.o.) in rats.
- Reduces intravenous cocaine self-administration in rats (12.5-25 mg/kg, i.p.).
- Inhibits basal and cocaine-enhanced locomotion in rats at 50 mg/kg.
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Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 | C12H13ClFN3OS | 100 MG
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Ro 41-1049 hydrochloride is a reversible and selective monoamine oxidase A (MAO-A) inhibitor used as a research reagent in neuropharmacology and biochemical studies. It is supplied as a white to off-white solid of high purity and is appropriate for both in vitro and in vivo experimental work.
- Selective reversible inhibition of MAO-A for mechanism-of-action studies.
- High purity suitable for analytical and pharmacological assays.
- Solid form simplifies handling and storage.
- Available in small research-scale quantities for dose-ranging studies.
- Well-characterized compound with CAS 127917-66-2 and a defined molecular weight.
- Useful for neurochemical and behavioral pharmacology experiments.
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Medchemexpress LLC Tenapanor hydrochloride | 1234365-97-9 | MFCD31631378 | 99.6% | 1217.97 | C50H68Cl6N8O10S2 | 10 MG
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Tenapanor hydrochloride is a potent, orally active sodium/hydrogen exchanger 3 (NHE3) inhibitor supplied for research use. It is provided as a white to off-white solid and is available in solid and solution formats for in vitro and in vivo studies.
- Potent NHE3 inhibitor for pharmacology and preclinical research.
- Provided as a white to off-white solid and as solution formulations.
- Reported purity 99.6% with analytical data (COA, HPLC, LCMS) available.
- Soluble in DMSO and water; formulation protocols give clear solutions ≥ 5 mg/mL.
- Recommended storage: 4°C sealed, away from moisture and light; in solvent store at -80°C for long-term.
- For research use only; not for human use or sale to patients.
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Medchemexpress LLC Agn 192403 hydrochloride | 1021868-90-5 | 99.0% | 189.73 g/mol | C10H20ClN | 5 MG
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AGN 192403 hydrochloride is the hydrochloride salt of a selective I1-imidazoline receptor antagonist used in cardiovascular and neurological research. It is supplied in small research quantities with high reported purity, and includes solubility and formulation guidance for in vitro and in vivo studies.
- Selective I1-imidazoline receptor antagonist for receptor pharmacology studies.
- Hydrochloride salt form improves solubility in polar solvents.
- High purity suitable for biochemical and cellular assays.
- Available in small milligram quantities for preclinical research.
- Soluble in DMSO; in vivo formulation recipes and concentrations are reported.
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Medchemexpress LLC Nordoxepin hydrochloride | 2887-91-4 | 99.9% | 301.81 g/mol | C18H20ClNO | 10 MG
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Nordoxepin hydrochloride is the primary metabolite of the tricyclic antidepressant doxepin and is provided as a solid research reagent for analytical, pharmacological, and metabolic studies. It is supplied with characterized purity and storage recommendations and is intended for research use only (not for human or veterinary use).
- Chemical identity: CAS 2887-91-4; formula C18H20ClNO; MW 301.81 g/mol.
- High purity (99.94%).
- Appearance: solid; store sealed and away from moisture.
- Storage in solvent: -80°C up to 6 months; -20°C up to 1 month.
- Intended applications: analytical and pharmacokinetic research.
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Medchemexpress LLC Bevantolol hydrochloride | 42864-78-8 | 10 MG
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Bevantolol hydrochloride is a beta-1 and alpha-1 adrenergic receptor antagonist supplied as an analytical standard for laboratory research in adrenergic pharmacology.
- Selective β1 and α1 adrenergic receptor antagonist.
- Supplied as an analytical standard for research use.
- CAS number 42864-78-8.
- Molecular formula C20H28ClNO4; molecular weight 381.89 g/mol.
- Available in small milligram pack sizes, including 10 MG for analytical applications.
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